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Light Scattering Detector Product List

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Multifaceted evaluation to ensure the quality and safety of antibody pharmaceuticals.

Multifaceted evaluation to ensure the quality and safety of antibody pharmaceuticals.

High-precision measurement of size variants, aggregates, and stability using light scattering detectors and LC-MS.

In the development of antibody drugs and antibody-drug conjugates (ADCs, etc.), it is essential to maximize the efficiency of the development process while ensuring the quality and safety of the products. By using light scattering detectors to evaluate size variants, aggregates, stability, and other factors from the early stages of development, it is possible to identify the characteristics of potential candidate antibodies early on and avoid risks and dropouts in the later stages of development. Combining this with LC-MS allows for even more comprehensive characterization. By clicking "Submit," you are deemed to have agreed to Waters' use and processing of the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

  • Light Scattering Photometer
  • High Performance Liquid Chromatograph
  • Mass Spectrometer

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Evaporative Light Scattering Detector Biotage ELSD-A120

Evaporative Light Scattering Detector Biotage ELSD-A120

By simultaneously monitoring with a UV detector and ELSD, the risk of missing compound fractions is significantly reduced.

The Biotage ELSD (evaporative light-scattering detector) is a universal detector used for purifying organic compounds that cannot be detected by ultraviolet or visible light. When combined with a flash purification system, it can fractionate and purify organic compounds, lipids, steroids, and other substances that lack ultraviolet absorption, which traditional UV detectors cannot detect.

  • Separation device
  • Other physicochemical equipment
  • Analytical Equipment and Devices

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Multi-Angle Light Scattering (MALS) Detector DAWN Series

Multi-Angle Light Scattering (MALS) Detector DAWN Series

High-precision measurement of absolute molecular weight in the range of hundreds to hundreds of millions Da for the characterization of polymers, proteins, and nanoparticles!

The DAWN series measures the molecular weight and size of macromolecules such as proteins with high precision, using multi-angle light scattering (MALS) without the need for calibration curves created from standard substances. It can be connected to HPLC and UPLC, enabling a wide range of applications. 【Features】 - DAWN (18-angle detector) offers high sensitivity and wide-range measurement. - A diverse lineup including DAWN8 (8-angle detector), miniDAWN (3-angle detector), microDAWN (UPLC-compatible model), and UltraDAWN (process-compatible model). - Automated cell cleaning with built-in ultrasonic cleaner COMET. - Equipped with a dynamic light scattering (DLS) module, allowing measurements from a radius of 0.5 nm (optional). - Real-time display of system status, with troubleshooting guidance functionality. By clicking [Send], you agree that the information provided on this site will be used and processed by Waters in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

  • Analytical Equipment and Devices
  • High Performance Liquid Chromatograph

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AAV, exosome quality control and manufacturing process optimization tool

AAV, exosome quality control and manufacturing process optimization tool

Accurate and efficient evaluation of critical quality attributes using light scattering detectors and LC-MS.

To ensure safe and effective treatment, monitoring of the potency and titer of adeno-associated virus (AAV) vectors, encapsulation, aggregation, genome integrity, and other factors is necessary. By combining SEC (size exclusion chromatography), IEX (ion exchange chromatography), and MALS (multi-angle static light scattering), it is possible to accurately and efficiently evaluate critical quality attributes (CQA) such as the Full/Empty ratio, aggregation, and particle concentration of AAV. RT-MALS allows for real-time measurement of these parameters, which is useful for streamlining the manufacturing process. By combining size separation and light scattering analysis, exosomes can be isolated from other biological components, enabling the detection of new subtypes based on size, composition, charge, and even functional differences, allowing for comprehensive characterization. LC-MS enables the identification and quantification of gene sequences and proteins contained in AAV vectors. By clicking [Submit], you are deemed to have agreed that Waters may use and process the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

  • Light Scattering Photometer
  • High Performance Liquid Chromatograph
  • Chromatography Consumables

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